Description

2-Pyridinepropanenitrile,β-Hydroxy-,(Betas)-(9Ci) is a specialized chiral nitrile compound with a pyridine backbone and a hydroxyl functional group. This unique molecular architecture makes it a valuable versatile building block for synthesizing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought by research institutions, pharmaceutical R&D labs, and fine chemical manufacturers engaged in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced, high-efficacy pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric catalysis.
• Academic and Industrial Research: Employed in chemical research for studying reaction mechanisms and developing new synthetic methodologies.
• Fine Chemical Production: A building block for manufacturing specialty chemicals with specific optical activity.

Basic Information

Product Name	2-Pyridinepropanenitrile,β-Hydroxy-,(Betas)-(9Ci)
CAS No.	676563-18-1
Molecular Formula	C8H8N2O
Molecular Weight	148.16 g/mol
Synonyms	(βS)-β-Hydroxy-2-pyridinepropanenitrile; (S)-3-Hydroxy-3-(pyridin-2-yl)propanenitrile; (S)-2-Pyridinepropanenitrile, β-hydroxy-; (S)-3-(Pyridin-2-yl)-3-hydroxypropanenitrile; β-Hydroxy-2-pyridinepropanenitrile (Betas); 2-Pyridinepropanenitrile, β-hydroxy-, (βS)-; (S)-3-Hydroxy-3-(2-pyridyl)propionitrile
EINECS	Contact for details

Quality Control

Our production of 2-Pyridinepropanenitrile,β-Hydroxy-,(Betas)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analysis, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and IR spectroscopy for structural confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.