Description

Cyclohexanecarboxylic Acid, 4-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-, Ethyl Ester is a high-purity, protected intermediate of significant value in advanced organic synthesis. This compound is specifically engineered to provide a silyl-protected hydroxyl group on the cyclohexane ring, offering enhanced stability and selectivity during complex chemical transformations. It is a critical building block for research and development chemists in the pharmaceutical and agrochemical industries, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Advanced Material Research: Serves as a precursor for liquid crystals, specialty polymers, and other functional materials with tailored properties.
• Organic Synthesis Building Block: Facilitates the introduction of a functionalized cyclohexane moiety in medicinal chemistry and total synthesis projects.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes due to the stability imparted by the tert-butyldimethylsilyl (TBDMS) protecting group.
• Academic & Contract Research: A valuable reagent for methodological development and the exploration of new catalytic or asymmetric reactions.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 4-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-, Ethyl Ester
CAS No.	676560-15-9
Molecular Formula	C16H32O3Si
Molecular Weight	300.52 g/mol
Synonyms	Ethyl 4-[(tert-Butyldimethylsilyl)oxy]cyclohexanecarboxylate; 4-[(tert-Butyldimethylsilyl)oxy]cyclohexanecarboxylic Acid Ethyl Ester; Ethyl 4-(TBDMS-oxy)cyclohexanecarboxylate; 4-(tert-Butyldimethylsiloxy)cyclohexanecarboxylic Acid Ethyl Ester; TBDMS-protected Ethyl 4-Hydroxycyclohexanecarboxylate; 4-OTBDMS-Cyclohexanecarboxylic Acid Ethyl Ester; Ethyl trans/cis-4-[(tert-Butyldimethylsilyl)oxy]cyclohexanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 4-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.