Description

6-(4-Formyl-3-Methoxyphenoxy)Nicotinonitrile is a high-purity, multifunctional chemical intermediate with a distinct molecular architecture. This compound matters for its role as a versatile building block in the synthesis of complex, high-value molecules, particularly within advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its phenoxy and nitrile functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as novel polymers and small molecules for OLEDs or sensors.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	6-(4-Formyl-3-Methoxyphenoxy)Nicotinonitrile
CAS No.	676495-33-3
Molecular Formula	C14H10N2O3
Molecular Weight	254.24 g/mol
Synonyms	6-(4-Formyl-3-methoxyphenoxy)pyridine-3-carbonitrile; 3-Pyridinecarbonitrile, 6-[(4-formyl-2-methoxyphenyl)oxy]-; 6-(4-Formyl-3-methoxyphenoxy)-3-pyridinecarbonitrile; Nicotinonitrile, 6-(4-formyl-3-methoxyphenoxy)-; 6-(4-Formyl-2-methoxyphenoxy)nicotinonitrile; (4-Formyl-3-methoxyphenoxy)nicotinonitrile; Building Block 676495-33-3
EINECS	Contact for details

Quality Control

Our 6-(4-Formyl-3-Methoxyphenoxy)Nicotinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.