Description

1,2-Cyclopropanedimethanol,1-Fluoro-,Alpha2-Acetate,(1R,2S)-Rel-(9Ci) is a high-purity, stereochemically defined fluorinated cyclopropane derivative. This compound is valued as a sophisticated chiral building block and intermediate in advanced organic synthesis, offering precise structural control for complex molecule construction. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting specific biological pathways.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and pesticides, where the fluorinated cyclopropane moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials with tailored properties.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study enzyme mechanisms and biological interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	1,2-Cyclopropanedimethanol,1-Fluoro-,Alpha2-Acetate,(1R,2S)-Rel-(9Ci)
CAS No.	676329-14-9
Molecular Formula	C8H13FO3
Molecular Weight	176.18 g/mol
Synonyms	(1R,2S)-rel-1-Fluoro-1,2-cyclopropanedimethanol α2-acetate; 1-Fluoro-1,2-cyclopropanedimethanol acetate (rel-(1R,2S)-); Fluorocyclopropane dimethanol acetate derivative; Chiral fluorocyclopropane building block; (1R,2S)-1-Fluoro-2-(hydroxymethyl)cyclopropylmethyl acetate; 676329-14-9; rel-(1R,2S)-1-Fluoro-1,2-cyclopropanedimethanol α-acetate
EINECS	Contact for details

Quality Control

Our production of 1,2-Cyclopropanedimethanol,1-Fluoro-,Alpha2-Acetate,(1R,2S)-Rel-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure consistency and meet the exacting standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (rel-(1R,2S))
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.