Description

1-(2-Hydroxy-Ethyl)-4,6-Dimethyl-2-Oxo-1,2-Dihydro-Pyridine-3-Carbonitrile is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a nitrile group and a hydroxylethyl side chain, makes it a versatile intermediate for constructing complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional dyes due to its electron-withdrawing nitrile group.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A valuable intermediate for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	1-(2-Hydroxy-Ethyl)-4,6-Dimethyl-2-Oxo-1,2-Dihydro-Pyridine-3-Carbonitrile
CAS No.	675843-82-0
Molecular Formula	C₁₀H₁₂N₂O₂
Molecular Weight	192.22 g/mol
Synonyms	2-Oxo-1,2-dihydro-1-(2-hydroxyethyl)-4,6-dimethylpyridine-3-carbonitrile; 1-(2-Hydroxyethyl)-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile; 3-Cyano-1-(2-hydroxyethyl)-4,6-dimethyl-2(1H)-pyridinone; 4,6-Dimethyl-1-(2-hydroxyethyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile; 1-(2-Hydroxyethyl)-4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile; 3-Pyridinecarbonitrile, 1,2-dihydro-1-(2-hydroxyethyl)-4,6-dimethyl-2-oxo-; HEDP-CN (common abbreviation)
EINECS	Contact for details

Quality Control

Our 1-(2-Hydroxy-Ethyl)-4,6-Dimethyl-2-Oxo-1,2-Dihydro-Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) documenting all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.