Description

3-Bromo-5-(4-Fluorophenyl)Pyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine core.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Ligand Preparation: Utilized in the synthesis of novel nitrogen-containing ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and tools to study biological processes.

Basic Information

Product Name	3-Bromo-5-(4-Fluorophenyl)Pyridine
CAS No.	675590-04-2
Molecular Formula	C11H7BrFN
Molecular Weight	252.08 g/mol
Synonyms	5-(4-Fluorophenyl)-3-bromopyridine; 3-Bromo-5-(p-fluorophenyl)pyridine; 3-Bromo-5-(4-fluorophenyl)pyridine; 675590-04-2; 5-(4-Fluorophenyl)-3-bromo-pyridine; 3-Bromo-5-(4'-fluorophenyl)pyridine; (4-Fluorophenyl)-3-bromo-5-pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(4-Fluorophenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and REACH requirements for our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.