Description

3-Bromo-5-(4-Trifluoromethylphenyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethylphenyl substituents. This compound is essential for facilitating advanced molecular construction in research and development, offering precise reactivity for cross-coupling and functionalization. It is primarily sought after by pharmaceutical, agrochemical, and advanced materials chemists for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine and trifluoromethyl motifs.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Negishi, and other palladium-catalyzed coupling reactions to form complex biaryl structures.
• Ligand and Catalyst Development: Utilized in the synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	3-Bromo-5-(4-Trifluoromethylphenyl)Pyridine
CAS No.	675590-01-9
Molecular Formula	C12H7BrF3N
Molecular Weight	302.09 g/mol
Synonyms	3-Bromo-5-[4-(trifluoromethyl)phenyl]pyridine; 5-(4-Trifluoromethylphenyl)-3-bromopyridine; 3-Bromo-5-(4-trifluoromethylphenyl)pyridine; 3-Bromo-5-(alpha,alpha,α-trifluoro-p-tolyl)pyridine; Pyridine, 3-bromo-5-[4-(trifluoromethyl)phenyl]-; 675590-01-9
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay and impurity profiles are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.