Description

3-Bromo-5-(2-Trifluoromethylphenyl)Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters because its unique structure, featuring both bromine and trifluoromethylphenyl substituents, provides versatile reactivity for constructing complex molecules with tailored properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as drug discovery, material science, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for developing organic electronic materials, including ligands for metal-organic frameworks (MOFs) and components for organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi, Stille) to form biaryl structures.
• Ligand and Catalyst Development: Utilized in the synthesis of novel nitrogen-containing ligands for asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	3-Bromo-5-(2-Trifluoromethylphenyl)Pyridine
CAS No.	675589-99-8
Molecular Formula	C12H7BrF3N
Molecular Weight	302.09 g/mol
Synonyms	3-Bromo-5-(2-(trifluoromethyl)phenyl)pyridine; 5-Bromo-3-(2-trifluoromethylphenyl)pyridine; [2-(Trifluoromethyl)phenyl]-5-bromopyridine; 2-(3-Bromopyridin-5-yl)benzotrifluoride; 3-Bromo-5-(α,α,α-trifluoro-o-tolyl)pyridine; Pyridine, 3-bromo-5-[2-(trifluoromethyl)phenyl]-; 675589-99-8
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(2-Trifluoromethylphenyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.