Description

3-Bromo-5-(3-Trifluoromethyl-Phenyl)-Pyridine is a high-value, multi-functional heterocyclic building block. This compound is specifically engineered for advanced organic synthesis, offering a unique combination of a bromo-substituted pyridine core and a trifluoromethylphenyl group. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Serves as a critical building block for developing new herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine and trifluoromethyl motifs.
• Material Science: Used in the research and development of advanced organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig cross-coupling reactions to create complex biaryl structures.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis in asymmetric synthesis and transition metal complexes.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	3-Bromo-5-(3-Trifluoromethyl-Phenyl)-Pyridine
CAS No.	675589-94-3
Molecular Formula	C12H7BrF3N
Molecular Weight	302.09 g/mol
Synonyms	3-Bromo-5-[3-(trifluoromethyl)phenyl]pyridine; 5-(3-Trifluoromethylphenyl)-3-bromopyridine; [3-Bromo-5-(3-trifluoromethylphenyl)]pyridine; 3-Bromo-5-(α,α,α-trifluoro-m-tolyl)pyridine; 3-Bromo-5-(m-trifluoromethylphenyl)pyridine; Pyridine, 3-bromo-5-[3-(trifluoromethyl)phenyl]-; 675589-94-3
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(3-Trifluoromethyl-Phenyl)-Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.