Description

4-Piperidinecarboxylic Acid, 1-(Aminothioxomethyl)-, Ethyl Ester is a specialized piperidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both ester and thioamide functionalities, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Synthesis: Serves as a versatile building block for creating complex piperidine-based compounds, peptidomimetics, and other specialty chemicals.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new chemical reactions and pathways.
• Material Science: Potential intermediate for the synthesis of functional polymers or ligands for catalysis.

Basic Information

Product Name	4-Piperidinecarboxylic Acid, 1-(Aminothioxomethyl)-, Ethyl Ester
CAS No.	675149-01-6
Molecular Formula	C10H18N2O2S
Molecular Weight	230.33 g/mol
Synonyms	Ethyl 1-(aminothioxomethyl)piperidine-4-carboxylate; 1-Carbamothioylpiperidine-4-carboxylic acid ethyl ester; 4-Carbethoxy-1-thiocarbamoylpiperidine; Piperidine-4-carboxylic acid, 1-(aminothioxomethyl)-, ethyl ester; 1-Thiocarbamoyl-4-piperidinecarboxylic acid ethyl ester; Ethyl 4-piperidinecarboxylate-1-carbothioamide
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for this intermediate typically meets a purity specification of ≥95% (by HPLC), with specifications for key impurities available. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent levels is provided with each shipment. We can support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.