Description

3,4,5-Pyridinetriol, 2,3,4,5-Tetrahydro-2-(Hydroxymethyl)-6-(Propylamino)-, (2R,3R,4S,5S)- (9Ci) is a high-purity, stereochemically defined pyridine derivative with significant potential in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the development of novel pharmaceuticals and bioactive molecules with precise three-dimensional structures. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapies.
• Agrochemical Research: Used in the synthesis of advanced, targeted pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex natural product analogs and specialty chemicals.
• Biochemical Probe Development: Employed in medicinal chemistry to design and synthesize molecular probes for studying enzyme mechanisms and receptor interactions.
• Academic & Institutional Research: A valuable compound for universities and research institutes conducting studies in asymmetric synthesis and heterocyclic chemistry.
• Catalyst Ligand Precursor: Potential use in the development of chiral ligands for asymmetric catalysis applications.

Basic Information

Product Name	3,4,5-Pyridinetriol, 2,3,4,5-Tetrahydro-2-(Hydroxymethyl)-6-(Propylamino)-, (2R,3R,4S,5S)- (9Ci)
CAS No.	675130-10-6
Molecular Formula	C9H18N2O4
Molecular Weight	218.25 g/mol
Synonyms	(2R,3R,4S,5S)-2,3,4,5-Tetrahydro-2-(hydroxymethyl)-6-(propylamino)-3,4,5-pyridinetriol; (2R,3R,4S,5S)-6-(Propylamino)-2-(hydroxymethyl)piperidine-3,4,5-triol; 2,3,4,5-Tetrahydro-2-(hydroxymethyl)-6-(propylamino)-3,4,5-pyridinetriol, (2R,3R,4S,5S)-; 1-Deoxy-1-(propylamino)-D-mannitol (related analog); A stereoisomer of 1-Deoxy-1-(propylamino)hexitol.
EINECS	Contact for details

Quality Control

Our production of 3,4,5-Pyridinetriol, 2,3,4,5-Tetrahydro-2-(Hydroxymethyl)-6-(Propylamino)-, (2R,3R,4S,5S)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high stereochemical integrity and chemical purity suitable for research and development applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (2R,3R,4S,5S)-isomer
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.