Description

Butanoic Acid, 4,4,4-Trifluoro-3-(Trifluoromethyl)-, Methyl Ester is a high-value, multi-fluorinated organic ester characterized by its unique perfluoroalkyl side chain. This compound is a critical synthetic intermediate and building block, prized for introducing lipophilicity and metabolic stability into target molecules. It is primarily utilized by the pharmaceutical, agrochemical, and advanced materials industries for research and development, as well as process-scale manufacturing.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and CNS-targeted therapies.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers, coatings, and liquid crystals with enhanced chemical resistance and thermal stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and nucleophilic substitutions to construct complex fluorinated architectures in medicinal and material chemistry.
• Chemical Research & Development: Essential for academic and industrial R&D labs exploring new fluorination methodologies and the properties of fluorine-containing compounds.

Basic Information

Product Name	Butanoic Acid, 4,4,4-Trifluoro-3-(Trifluoromethyl)-, Methyl Ester
CAS No.	674335-88-7
Molecular Formula	C7H6F6O2
Molecular Weight	236.11 g/mol
Synonyms	Methyl 4,4,4-Trifluoro-3-(trifluoromethyl)butanoate; 4,4,4-Trifluoro-3-(trifluoromethyl)butyric Acid Methyl Ester; 3-(Trifluoromethyl)-4,4,4-trifluorobutanoic Acid Methyl Ester; Methyl Perfluoroisovalerate; Methyl 3-(Trifluoromethyl)-4,4,4-trifluorobutyrate; Butanoic Acid, 4,4,4-Trifluoro-3-(trifluoromethyl)-, Methyl Ester
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 4,4,4-Trifluoro-3-(Trifluoromethyl)-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global clientele in regulated industries. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.