Description

Pyridine, 4-Isocyanato-, 1-Oxide (9Ci) is a specialized heterocyclic building block that combines an isocyanate functional group with an N-oxide moiety on a pyridine scaffold. This unique structure makes it a valuable intermediate for synthesizing advanced materials and bioactive compounds where precise chemical functionality is critical. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced polymer industries for creating novel molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those targeting specific receptors where the pyridine N-oxide and isocyanate groups can be leveraged for binding or as a synthetic handle.
• Agrochemical Research: Serves as a key precursor in developing new herbicides, fungicides, or insecticides with enhanced activity and selectivity.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers, polyurethanes, or coatings with unique thermal, mechanical, or surface properties.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalysis, leveraging the coordinating ability of the N-oxide group.
• Chemical Biology Probes: Employed in the design of activity-based probes or bioconjugation reagents for studying biological processes.

Basic Information

Product Name	Pyridine, 4-Isocyanato-, 1-Oxide (9Ci)
CAS No.	674297-85-9
Molecular Formula	C6H4N2O2
Molecular Weight	136.11 g/mol
Synonyms	4-Isocyanatopyridine 1-Oxide; 4-Isocyanatopyridine N-Oxide; 1-Oxido-4-pyridinyl isocyanate; Pyridine-4-isocyanate N-oxide; 4-Pyridyl isocyanate N-oxide; Isocyanic acid, 4-pyridinyl ester, 1-oxide; 4-NCO-Pyridine N-oxide
EINECS	Contact for details

Quality Control

Our production of Pyridine, 4-Isocyanato-, 1-Oxide (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your research and development. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.