Description

5-(4-Fluorophenoxy)Pyridin-2-Amine is a high-purity organic intermediate featuring a pyridine core substituted with a fluorophenoxy group. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where its specific structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides that require fluorinated aromatic systems.
• Material Science Research: Used in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and diagnostic agents in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	5-(4-Fluorophenoxy)Pyridin-2-Amine
CAS No.	672945-75-4
Molecular Formula	C11H9FN2O
Molecular Weight	204.20 g/mol
Synonyms	5-(4-Fluorophenoxy)-2-pyridinamine; 2-Amino-5-(4-fluorophenoxy)pyridine; 5-(p-Fluorophenoxy)pyridin-2-amine; 672945-75-4; 5-(4-Fluorophenoxy)-2-aminopyridine; 2-Pyridinamine, 5-(4-fluorophenoxy)-; 5-(4-Fluorophenoxy)pyridin-2-ylamine
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenoxy)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.