Description

(4-Aminomethyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected amine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and scale-up.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in high-throughput screening libraries and structure-activity relationship (SAR) studies to explore new chemical entities.
• Peptidomimetic Synthesis: Serves as a protected amino-pyridine moiety for constructing peptide analogs and bioisosteres.
• Agrochemical Development: Employed as a building block in the research and synthesis of novel crop protection agents and herbicides.
• Ligand and Catalyst Preparation: Useful for creating specialized nitrogen-containing ligands for metal catalysis and coordination chemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis projects.

Basic Information

Product Name	(4-Aminomethyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	672324-83-3
Molecular Formula	C11H17N3O2
Molecular Weight	223.27 g/mol
Synonyms	tert-Butyl N-[(2-pyridin-4-ylmethyl)amino]carbamate; N-(tert-Butoxycarbonyl)-4-(aminomethyl)pyridin-2-amine; 2-[(tert-Butoxycarbonyl)amino]-4-(aminomethyl)pyridine; Boc-4-Aminomethyl-2-aminopyridine; 4-(Aminomethyl)pyridin-2-yl-carbamic acid tert-butyl ester; 4-(Boc-amino)methyl-2-aminopyridine; 2-Amino-4-aminomethylpyridine Boc-derivative
EINECS	Contact for details

Quality Control

Our (4-Aminomethyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring material that meets internal quality standards or specific pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccator or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.