Description

β-Oxo-1-Cbz-2-Piperidinepropanoic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine and carbobenzyloxy (Cbz) protecting group functionalities. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents targeting the central nervous system. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process development, and scale-up production.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block for the production of complex pharmaceutical compounds, especially those with piperidine-based structures.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, particularly for neurological and psychiatric disorders.
• Process Chemistry & Scale-Up: Employed in the development and optimization of robust, scalable synthetic routes for commercial pharmaceutical manufacturing.
• Peptidomimetic Development: Acts as a scaffold in the design and synthesis of peptidomimetics and other bioactive molecules.
• Custom Synthesis Projects: Supplied for bespoke chemical synthesis services targeting specific client requirements in drug development pipelines.

Basic Information

Product Name	β-Oxo-1-Cbz-2-Piperidinepropanoic Acid Ethyl Ester
CAS No.	672323-15-8
Molecular Formula	C18H23NO5
Molecular Weight	333.38 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-2-oxo-3-piperidinepropanoic acid ethyl ester; Ethyl 1-Cbz-2-oxo-3-piperidinepropanoate; Ethyl 3-(1-(((benzyloxy)carbonyl)-2-oxopiperidin-3-yl)propanoate; 3-(1-(((Benzyloxy)carbonyl)-2-oxopiperidin-3-yl)propanoic acid ethyl ester; 1-Cbz-2-oxo-3-piperidinepropionic acid ethyl ester; N-Carbobenzyloxy-2-oxo-3-piperidinepropanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our β-Oxo-1-Cbz-2-Piperidinepropanoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and intermediate use. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.