Description

tert-Butyl 3-(2-Hydroxyethoxy)propanoate is a specialized bifunctional ester compound, serving as a valuable intermediate in advanced organic synthesis. Its structure, featuring both a protected carboxylic acid group and a terminal hydroxyl group, makes it a versatile building block for creating complex molecules with tailored properties. This chemical is particularly relevant for research and development chemists and process engineers in the pharmaceutical and fine chemical industries seeking to introduce specific functional groups or create novel polymer backbones.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring polyether or ester linkages.
• Polymer & Material Science: Monomer or co-monomer for producing specialty polyesters, polyethers, and biodegradable polymers with controlled hydrophilicity.
• Prodrug Synthesis: Utilized in designing prodrugs where the tert-butyl ester acts as a protecting group that can be cleaved under specific physiological conditions.
• Linker Chemistry: Serves as a spacer or linker molecule in bioconjugation and the development of antibody-drug conjugates (ADCs).
• Fine Chemical Synthesis: Intermediate for manufacturing agrochemicals, dyes, and performance chemicals requiring ethoxy and ester functionalities.
• Crosslinking Agent: Potential use in formulating coatings, adhesives, and sealants where its dual functionality can contribute to network formation.

Basic Information

Item	Details
Product Name	tert-Butyl 3-(2-Hydroxyethoxy)propanoate
CAS No.	671802-00-9
Molecular Formula	C9H18O4
Molecular Weight	190.24 g/mol
Synonyms	3-(2-Hydroxyethoxy)propanoic acid tert-butyl ester; 2-[2-(tert-Butoxy)-2-oxoethoxy]ethanol; tert-Butyl 3-(2-hydroxyethoxy)propionate; 1,2-Ethanediol, 2-[2-(1,1-dimethylethoxy)-2-oxoethoxy]-; Propanoic acid, 3-(2-hydroxyethoxy)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(2-Hydroxyethoxy)propanoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong acids and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.