Description

5-[1,3]Dioxolan-2-Yl-Pyridine-2-Carbonitrile is a versatile heterocyclic building block featuring both a dioxolane-protected aldehyde equivalent and a nitrile functional group. This compound is valued for its role as a key synthetic intermediate in the development of complex organic molecules, particularly in pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A key building block for custom synthesis houses serving the global pharmaceutical and biotechnology sectors.

Basic Information

Product Name	5-[1,3]Dioxolan-2-Yl-Pyridine-2-Carbonitrile
CAS No.	671776-91-3
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	2-Cyano-5-(1,3-dioxolan-2-yl)pyridine; 5-(1,3-Dioxolan-2-yl)picolinonitrile; 2-Pyridinecarbonitrile, 5-(1,3-dioxolan-2-yl)-; 5-(1,3-Dioxolan-2-yl)-2-cyanopyridine; 5-(2,2-Dimethyl-1,3-dioxolan-4-yl)pyridine-2-carbonitrile (isomer); Picolinonitrile, 5-(1,3-dioxolan-2-yl)-
EINECS	Contact for details

Quality Control

Every batch of 5-[1,3]Dioxolan-2-Yl-Pyridine-2-Carbonitrile is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.