Description

1-(3-Nitropyridin-2-Yl)Piperidine-4-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its nitropyridine and piperidine-carbonitrile functional groups. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Employed in the construction of complex heterocyclic compounds due to its reactive nitropyridine and carbonitrile moieties.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents and pesticides.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical reactions.

Basic Information

Product Name	1-(3-Nitropyridin-2-Yl)Piperidine-4-Carbonitrile
CAS No.	671191-99-4
Molecular Formula	C11H12N4O2
Molecular Weight	232.24 g/mol
Synonyms	1-(3-Nitropyridin-2-yl)piperidine-4-carbonitrile; 2-(4-Cyanopiperidin-1-yl)-3-nitropyridine; 4-Cyano-1-(3-nitro-2-pyridinyl)piperidine; Piperidine-4-carbonitrile, 1-(3-nitro-2-pyridinyl)-; 1-(3-Nitro-2-pyridyl)piperidine-4-carbonitrile; 3-Nitro-2-(4-cyanopiperidin-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(3-Nitropyridin-2-Yl)Piperidine-4-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.