Description

5-Bromo-3-Fluoropicolinamide is a high-purity fluorinated and brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine core with halogen substituents.
• Chemical Synthesis Reagent: Serves as a versatile precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) or nucleophilic substitution.
• Material Science Research: Employed in the creation of novel organic ligands for catalysis or functional materials due to its distinct electronic properties.
• Academic & R&D: Utilized in university and corporate laboratories for methodological studies and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	5-Bromo-3-Fluoropicolinamide
CAS No.	669066-90-4
Molecular Formula	C6H4BrFN2O
Molecular Weight	219.01 g/mol
Synonyms	5-Bromo-3-fluoropyridine-2-carboxamide; 3-Fluoro-5-bromopicolinamide; 2-Pyridinecarboxamide, 5-bromo-3-fluoro-; 5-Bromo-3-fluoro-2-pyridinecarboxamide; 5-Bromo-3-fluoropyridine-2-carboxylic acid amide; 669066-90-4; 5-Br-3-F-picolinamide
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Fluoropicolinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.