Description

Spiro[2.4]Heptane-1-Carboxylic Acid, 1-Amino-, Methyl Ester (9Ci) is a specialized spirocyclic organic building block featuring a constrained bicyclic framework and both amino and ester functional groups. This unique molecular architecture is critical for modulating the three-dimensional shape, rigidity, and pharmacokinetic properties of advanced pharmaceutical candidates. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the design and production of novel pesticides and herbicides, where its spiro structure can contribute to unique biological activity and selectivity.
• Chemical Biology & Proteomics: Employed as a molecular probe or a building block for activity-based protein profiling (ABPP) and other biochemical tools.
• Material Science Research: Acts as a precursor for novel polymers or ligands with specific steric and electronic properties.
• Asymmetric Catalysis: Can be utilized as a chiral auxiliary or ligand precursor in stereoselective synthesis.
• Academic & Contract Research: Essential for synthetic organic chemistry research in universities and CROs (Contract Research Organizations) exploring new chemical spaces.

Basic Information

Product Name	Spiro[2.4]Heptane-1-Carboxylic Acid, 1-Amino-, Methyl Ester (9Ci)
CAS No.	669058-67-7
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	1-Amino-spiro[2.4]heptane-1-carboxylic acid methyl ester; Methyl 1-amino-spiro[2.4]heptane-1-carboxylate; Methyl 1-aminospiro[2.4]heptane-1-carboxylate; 1-Amino-1-(methoxycarbonyl)spiro[2.4]heptane; Spiro[2.4]heptane-1-carboxylic acid, 1-amino-, methyl ester; (1-Amino-spiro[2.4]heptan-1-yl)-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Spiro[2.4]Heptane-1-Carboxylic Acid, 1-Amino-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as NMR, HPLC, and GC to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and moisture. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.