Description

Spiro[2.4]Heptane-1-Carboxylic Acid, 1-Nitro-, Methyl Ester (9Ci) is a specialized nitro-substituted spirocyclic ester, a high-value intermediate for advanced organic synthesis. Its unique strained spiro[2.4]heptane framework and functional groups make it a critical building block for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, where its specific stereochemistry and reactivity are leveraged.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the spirocyclic structure can contribute to unique modes of action and environmental profiles.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis, enhancing stereoselectivity in critical synthetic steps.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of advanced polymers with specific thermal or mechanical properties.
• Academic & Discovery Chemistry: A valuable tool for methodology development and exploring new chemical space in organic synthesis laboratories worldwide.

Basic Information

Product Name	Spiro[2.4]Heptane-1-Carboxylic Acid, 1-Nitro-, Methyl Ester (9Ci)
CAS No.	669058-49-5
Molecular Formula	C9H13NO4
Molecular Weight	199.20 g/mol
Synonyms	Methyl 1-Nitrosipro[2.4]heptane-1-carboxylate; 1-Nitrosipro[2.4]heptane-1-carboxylic Acid Methyl Ester; Spiro[2.4]heptane-1-carboxylic acid, 1-nitro-, methyl ester; Methyl 1-nitrospiro[2.4]heptane-1-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Spiro[2.4]Heptane-1-Carboxylic Acid, 1-Nitro-, Methyl Ester (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development processes. A detailed Certificate of Analysis (COA) with specifications for purity (typically by HPLC or GC), chiral purity (if applicable), and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid or clear to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥95.0% (Typical grade, higher purity available)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.