Description

Methyl 3-([(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino)Propanoate CAS NO 669058-18-8 is a key Fmoc-protected amino acid derivative, specifically the methyl ester of Fmoc-β-alanine. This compound is essential for providing a protected β-alanine building block with an activated ester group, enabling efficient and controlled peptide chain elongation. It is primarily required by research institutions and pharmaceutical manufacturers engaged in solid-phase peptide synthesis (SPPS) for the development of novel therapeutic peptides, peptidomimetics, and biochemical probes. The product is supplied to meet the stringent purity demands of modern synthetic chemistry applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected building block for the automated or manual synthesis of peptides containing β-alanine residues.
• Pharmaceutical Intermediates: For the research and production of active pharmaceutical ingredients (APIs) based on peptide structures.
• Bioconjugation: Used in the synthesis of linker molecules or spacers for attaching peptides to other molecules, surfaces, or carriers.
• Peptidomimetic Drug Discovery: Serves as a crucial component in creating modified peptide analogs with enhanced stability or biological activity.
• Biochemical Research: For studying protein-protein interactions, enzyme substrates, and receptor ligands where a defined peptide sequence is required.
• Material Science: Potential use in creating peptide-based polymers or surface coatings with specific functional properties.

Basic Information

Product Name	Methyl 3-([(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino)Propanoate
CAS No.	669058-18-8
Molecular Formula	C19H19NO5
Molecular Weight	341.36 g/mol
Synonyms	Fmoc-β-Ala-OMe; Methyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-β-alaninate; Methyl 3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]propanoate; N-Fmoc-β-alanine methyl ester; (9-Fluorenylmethyloxycarbonyl)-β-alanine methyl ester; Fmoc-β-alanine methyl ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-β-alanine methyl ester; β-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-([(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino)Propanoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) detailing purity, chiral integrity (where applicable), and impurity profiles are available for every lot and provided upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.