Description

Methyl 5-(2-Fluorophenyl)Isoxazole-3-Carboxylate is a high-purity fluorinated isoxazole derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bioactivity of the fluorinated isoxazole scaffold.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Biology Probe Synthesis: Utilized to create labeled compounds or molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Methyl 5-(2-Fluorophenyl)Isoxazole-3-Carboxylate
CAS No.	668970-74-9
Molecular Formula	C11H8FNO3
Molecular Weight	221.19 g/mol
Synonyms	Methyl 5-(2-fluorophenyl)-1,2-oxazole-3-carboxylate; 3-Carbomethoxy-5-(2-fluorophenyl)isoxazole; 5-(2-Fluorophenyl)isoxazole-3-carboxylic acid methyl ester; Methyl 5-(o-fluorophenyl)isoxazole-3-carboxylate; 668970-74-9; 5-(2-Fluorophenyl)-3-(methoxycarbonyl)isoxazole
EINECS	Contact for details

Quality Control

Our Methyl 5-(2-Fluorophenyl)Isoxazole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.