Description

Ethyl 2-(5-Bromo-2-Fluorophenyl)-2-Oxoacetate is a high-purity, multifunctional organic building block essential for advanced chemical synthesis. This compound is valued for its reactive α-ketoester and halogenated aryl structure, enabling precise molecular construction. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic ring for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent in proteomics and medicinal chemistry research due to its reactive ketone functionality.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, bespoke organic molecules for clients.

Basic Information

Product Name	Ethyl 2-(5-Bromo-2-Fluorophenyl)-2-Oxoacetate
CAS No.	668969-68-4
Molecular Formula	C10H8BrFO3
Molecular Weight	275.07 g/mol
Synonyms	Ethyl (5-Bromo-2-fluorobenzoyl)formate; 2-Oxo-2-(5-bromo-2-fluorophenyl)acetic acid ethyl ester; Ethyl 5-Bromo-2-fluorobenzoylformate; 5-Bromo-2-fluorophenylglyoxylic acid ethyl ester; α-Keto-5-bromo-2-fluorophenylacetic acid ethyl ester; (5-Bromo-2-fluorophenyl)(oxo)acetic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-(5-Bromo-2-Fluorophenyl)-2-Oxoacetate is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with exacting purity standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.