Description

tert-Butyl 2-Amino-5-Bromobenzoate is a high-purity, protected benzoate derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of a reactive bromine atom and a protected amine group, enabling selective functionalization for complex molecule construction. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those containing substituted aniline or benzamide pharmacophores.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the bromine and amino functionalities allow for further derivatization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, dyes, and photoactive materials due to its electron-donating and accepting properties.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom chemical synthesis services targeting novel chemical entities for various industries.

Basic Information

Product Name	tert-Butyl 2-Amino-5-Bromobenzoate
CAS No.	668969-63-9
Molecular Formula	C11H14BrNO2
Molecular Weight	272.14 g/mol
Synonyms	5-Bromo-2-[(tert-butoxycarbonyl)amino]benzoic acid tert-butyl ester; 2-Amino-5-bromobenzoic acid tert-butyl ester; tert-Butyl 5-bromo-2-aminobenzoate; 5-Bromoanthranilic acid tert-butyl ester; Boc-5-Bromo-anthranilic acid tert-butyl ester; (tert-Butoxycarbonyl)-5-bromoanthranilic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Amino-5-Bromobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.