Description

1-(3-Nitropyridin-2-Yl)Piperidine-4-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its specific nitropyridine-piperidine carboxamide structure. This compound is essential for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel small molecule therapeutics.
• Chemical Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Academic & Institutional Research: Employed in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.
• Pre-clinical Development: Utilized in the production of compounds for pharmacological screening and pre-clinical testing phases.

Basic Information

Product Name	1-(3-Nitropyridin-2-Yl)Piperidine-4-Carboxamide
CAS No.	668462-40-6
Molecular Formula	C11H14N4O3
Molecular Weight	250.26 g/mol
Synonyms	1-(3-Nitropyridin-2-yl)piperidine-4-carboxamide; 4-Carbamoyl-1-(3-nitro-2-pyridyl)piperidine; Piperidine-4-carboxamide, 1-(3-nitropyridin-2-yl)-; 2-(4-Carbamoylpiperidin-1-yl)-3-nitropyridine; 1-(3-Nitro-2-pyridinyl)-4-piperidinecarboxamide; UNII-3K7V7F2J0S; 3K7V7F2J0S; AKOS025310647
EINECS	Contact for details

Quality Control

Our 1-(3-Nitropyridin-2-Yl)Piperidine-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.