Description

Methanone, (4-Fluorophenyl)[1-[2-Methoxy-2-(4-Nitrophenyl)Ethyl]-4-Piperidinyl]- is a specialized organic compound featuring a complex molecular architecture that combines fluorophenyl, nitrophenyl, and piperidinyl moieties. This structure makes it a valuable advanced pharmaceutical intermediate for the research and development of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapeutic research.
• Chemical Research & Development: Used as a precursor for creating novel chemical libraries in medicinal chemistry for high-throughput screening and structure-activity relationship (SAR) studies.
• Academic Research: Serves as a reference standard or starting material in university and institutional labs for studying complex organic reactions and heterocyclic chemistry.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for potential new APIs.
• Custom Synthesis: A critical substrate for contract research organizations (CROs) and CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	Methanone, (4-Fluorophenyl)[1-[2-Methoxy-2-(4-Nitrophenyl)Ethyl]-4-Piperidinyl]-
CAS No.	666859-49-0
Molecular Formula	C21H23FN2O4
Molecular Weight	386.42 g/mol
Synonyms	(4-Fluorophenyl){1-[2-methoxy-2-(4-nitrophenyl)ethyl]-4-piperidinyl}methanone; 1-[2-Methoxy-2-(4-nitrophenyl)ethyl]-4-(4-fluorobenzoyl)piperidine; 4-Fluorophenyl[1-[2-methoxy-2-(4-nitrophenyl)ethyl]-4-piperidinyl]methanone; 4'--Fluoro-2'--methoxy-4-nitro-α-piperidinopropiophenone; (4-Fluorophenyl)(1-(2-methoxy-2-(4-nitrophenyl)ethyl)piperidin-4-yl)methanone
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.