Description

2-Thiophenecarboxylic Acid, 5-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Methyl Ester is a high-value, multi-functional thiophene derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a protected amino group and an ester moiety, makes it an indispensable intermediate for constructing complex molecules with precision. This compound is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of conductive polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems used in cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) requiring specific, high-purity heterocyclic compounds.
• Chemical Biology & Proteomics: Utilized as a building block for creating chemical probes and affinity tags to study biological processes.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, 5-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Methyl Ester
CAS No.	666853-39-0
Molecular Formula	C12H15NO4S
Molecular Weight	269.32 g/mol
Synonyms	5-[(tert-Butoxycarbonyl)amino]thiophene-2-carboxylic acid methyl ester; Methyl 5-[(tert-butoxycarbonyl)amino]thiophene-2-carboxylate; Methyl 5-(Boc-amino)thiophene-2-carboxylate; Boc-5-Amino-2-thiophenecarboxylic Acid Methyl Ester; 5-(Boc-amino)-2-thiophenecarboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 5-[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester; t-Butyl N-(5-methoxycarbonyl-2-thienyl)carbamate
EINECS	Contact for details

Quality Control

Every batch of our 2-Thiophenecarboxylic Acid, 5-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Methyl Ester is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for pharmaceutical and fine chemical synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.