Description

Methyl 3-Isocyanopropionate is a versatile and reactive organic building block used in advanced chemical synthesis. This compound is valued for its isocyanate functional group, which readily undergoes addition reactions to form ureas, carbamates, and other valuable heterocyclic structures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds and active ingredients.

Application

• Pharmaceutical Intermediates: A key synthon for the preparation of urea and carbamate-based drug candidates, including protease inhibitors and kinase modulators.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides by incorporating the propionate-isocyanate motif.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialized polyurethanes and polyurea coatings with tailored properties.
• Peptide Mimetics & Bioconjugation: Facilitates the synthesis of peptide analogs and the conjugation of small molecules to proteins or other biomolecules.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new reaction pathways and creating compound libraries for screening.
• Material Science: Used in the surface functionalization of materials and the synthesis of advanced organic frameworks.

Basic Information

Product Name	Methyl 3-Isocyanopropionate
CAS No.	665054-33-1
Molecular Formula	C5H7NO3
Molecular Weight	129.11 g/mol
Synonyms	3-Isocyanatopropionic Acid Methyl Ester; Methyl β-Isocyanatopropionate; Methyl 3-Isocyanatopropanoate; 3-Isocyanato-propionic Acid Methyl Ester; Propanoic acid, 3-isocyanato-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Isocyanopropionate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity and NMR confirmation, to support your research and production requirements. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its moisture-sensitive (hygroscopic) nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent hydrolysis. Recommended storage temperature: 2-8°C for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.