Description

1-Piperidinecarboxylicacid,2-Ethyl-,1,1-Dimethylethylester,(2R)-(9Ci) is a chiral piperidine derivative, a high-value building block in advanced organic synthesis. Its defined stereochemistry and protected carboxylic acid functionality make it a critical intermediate for constructing complex molecules with precise spatial orientation. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where stereochemical purity is paramount for efficacy and safety.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and cardiovascular therapeutics.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific enantiomers exhibit enhanced biological activity.
• Asymmetric Catalysis: Serves as a precursor or ligand component in chiral catalysts for stereoselective chemical transformations.
• Peptidomimetics Research: Employed in medicinal chemistry to create conformationally restricted peptide analogs for improved metabolic stability and receptor binding.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes to study enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-Piperidinecarboxylicacid,2-Ethyl-,1,1-Dimethylethylester,(2R)-(9Ci)
CAS No.	664364-76-5
Molecular Formula	C12H23NO2
Molecular Weight	213.32 g/mol
Synonyms	(R)-2-Ethylpiperidine-1-carboxylic acid tert-butyl ester; tert-Butyl (R)-2-ethylpiperidine-1-carboxylate; (R)-1-Boc-2-ethylpiperidine; (2R)-2-Ethyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-2-ethyl-(R)-piperidine; BOC-(R)-2-Ethylpiperidine; 664364-76-5; (R)-N-Boc-2-ethylpiperidine
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high enantiomeric purity. Quality is verified through advanced analytical techniques including Chiral HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), chiral purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.