Description

4-[2-(1-Piperidinyl)Ethyl]-5-(4-Pyridinyl)-4H-1,2,4-Triazole-3-Thiol is a high-purity, heterocyclic organic compound featuring a unique triazole-thiol core functionalized with piperidine and pyridine moieties. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a key scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand Synthesis: The triazole-thiol and pyridine groups make it suitable for developing chelating agents or ligands for catalytic and biochemical applications.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme inhibition or protein-ligand interactions.
• Agrochemical Research: Investigated as an intermediate for developing new active ingredients with potential herbicidal or pesticidal activity.
• Material Science: Potential use as a monomer or additive in the synthesis of specialized polymers with unique thermal or chemical properties.

Basic Information

Item	Detail
Product Name	4-[2-(1-Piperidinyl)Ethyl]-5-(4-Pyridinyl)-4H-1,2,4-Triazole-3-Thiol
CAS No.	664308-41-2
Molecular Formula	C14H19N5S
Molecular Weight	289.40 g/mol
Synonyms	4-(2-Piperidin-1-ylethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol; 5-(4-Pyridinyl)-4-[2-(1-piperidinyl)ethyl]-4H-1,2,4-triazole-3-thiol; 4H-1,2,4-Triazole-3-thiol, 4-[2-(1-piperidinyl)ethyl]-5-(4-pyridinyl)-; CAS 664308-41-2; 4-(2-(Piperidin-1-yl)ethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol
EINECS	Contact for details

Quality Control

Our 4-[2-(1-Piperidinyl)Ethyl]-5-(4-Pyridinyl)-4H-1,2,4-Triazole-3-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere for long-term storage). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.