Description

4-Bromo-1-(2-Chloroethyl)-1H-Pyrazole is a versatile and high-purity halogenated pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional reactive sites make it an indispensable intermediate for constructing complex molecular architectures with high selectivity. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of new-generation herbicides, fungicides, and insecticides, leveraging its pyrazole core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on proprietary compounds.
• Academic & Industrial R&D: Essential for methodological studies in heterocyclic chemistry and for exploring new reaction pathways in process chemistry.

Basic Information

Product Name	4-Bromo-1-(2-Chloroethyl)-1H-Pyrazole
CAS No.	663941-72-8
Molecular Formula	C5H6BrClN2
Molecular Weight	209.47 g/mol
Synonyms	1-(2-Chloroethyl)-4-bromo-1H-pyrazole; 4-Bromo-1-(2-chloroethyl)pyrazole; 1H-Pyrazole, 4-bromo-1-(2-chloroethyl)-; 663941-72-8; 4-Bromo-1-(2-chloroethyl)pyrazole; 1-(2-Chloroethyl)-4-bromopyrazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-(2-Chloroethyl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.