Description

Cyclopenta[C]Pyrrole, 1,2,3,3A,4,6A-Hexahydro-5-(2-Methyl-3-Pyridinyl)-, (3Ar,6As)-Rel- (9Ci) is a complex, high-purity heterocyclic compound featuring a fused cyclopentapyrrole core substituted with a methylpyridinyl group. This specific stereochemistry and molecular architecture make it a critical advanced intermediate for pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of complex drug candidates, especially in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new chemical entities.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the efficient and cost-effective production of target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis methodology and the exploration of new heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	Cyclopenta[C]Pyrrole, 1,2,3,3A,4,6A-Hexahydro-5-(2-Methyl-3-Pyridinyl)-, (3Ar,6As)-Rel- (9Ci)
CAS No.	663173-73-7
Molecular Formula	C13H18N2
Molecular Weight	202.30 g/mol
Synonyms	rel-(3aR,6aS)-1,2,3,3a,4,6a-Hexahydro-5-(2-methylpyridin-3-yl)cyclopenta[c]pyrrole; 1,2,3,3a,4,6a-Hexahydro-5-(2-methyl-3-pyridinyl)cyclopenta[c]pyrrole, (3aR,6aS)-rel-; (rel-(3aR,6aS))-5-(2-Methyl-3-pyridinyl)-1,2,3,3a,4,6a-hexahydrocyclopenta[c]pyrrole; 663173-73-7; SCHEMBL218422; AKOS025247317; ZINC000103254757; A1-00832
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure identity, strength, and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development projects with GMP-grade material upon request for late-stage clinical and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥98.0% ee
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.