Description

tert-Butyl 3-(4-Methoxyphenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound serves as a critical building block for the synthesis of complex molecules targeting various therapeutic areas. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs). Our supply ensures consistent quality, reliable scalability, and full documentation to support your R&D and manufacturing processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chemical Biology Probe Development: Used to create tool compounds for studying specific biological pathways and target validation.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• API Synthesis: Integrated into multi-step synthetic routes for the production of complex, nitrogen-containing heterocyclic active ingredients.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for pioneering research in organic and medicinal chemistry.

Basic Information

Product Name	tert-Butyl 3-(4-Methoxyphenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
CAS No.	661487-36-1
Molecular Formula	C18H23N3O3
Molecular Weight	329.40 g/mol
Synonyms	5-tert-Butoxycarbonyl-3-(4-methoxyphenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine; 3-(4-Methoxyphenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester; tert-Butyl 3-(4-methoxyphenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-5-carboxylate; 1H-Pyrazolo[4,3-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-3-(4-methoxyphenyl)-, 1,1-dimethylethyl ester; CAS 661487-36-1
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(4-Methoxyphenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.