Description

tert-Butyl 3-Phenyl-6,7-Dihydro-1H-Pyrazolo[4,3-C]Pyridine-5(4H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Heterocyclic Compound Synthesis: Serves as a versatile building block for constructing complex fused pyrazole and pyridine ring systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel chemical entities.
• Chemical Library Development: Utilized in the creation of diverse screening libraries for high-throughput screening (HTS) against biological targets.
• Academic Research: Employed in university and institutional labs for studies in organic synthesis methodology and bioorganic chemistry.

Basic Information

Product Name	tert-Butyl 3-Phenyl-6,7-Dihydro-1H-Pyrazolo[4,3-C]Pyridine-5(4H)-Carboxylate
CAS No.	661487-18-9
Molecular Formula	C17H21N3O2
Molecular Weight	299.37 g/mol
Synonyms	5-tert-Butoxycarbonyl-3-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine; tert-Butyl 3-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-5-carboxylate; 1H-Pyrazolo[4,3-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-3-phenyl-, 1,1-dimethylethyl ester; 3-Phenyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylic acid tert-butyl ester; BOC-protected 3-phenyl-1,4,5,6,7,8-hexahydropyrazolo[4,3-c]pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Phenyl-6,7-Dihydro-1H-Pyrazolo[4,3-C]Pyridine-5(4H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.