Description

1,2-Piperidinedicarboxylic Acid, 6-Methyl-, 1-(1,1-Dimethylethyl) Ester (Wx610118) is a high-purity, synthetic organic compound belonging to the piperidine-dicarboxylate class, serving as a critical building block in advanced chemical synthesis. Its value lies in its role as a protected amino acid derivative, offering a versatile chiral scaffold for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds. The product, identified by CAS No. 661458-33-9, is supplied with stringent quality control to ensure batch-to-batch consistency for demanding R&D and scale-up processes.

Application

This specialized piperidine derivative is designed for high-value synthetic applications. Key uses include:

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used as a building block for developing novel pesticides and herbicides with specific stereochemical requirements.
• Peptidomimetics & PROTACs: Serves as a constrained amino acid analog in the design of peptide mimics and proteolysis-targeting chimeras (PROTACs).
• Catalyst & Ligand Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, advanced intermediates.

Basic Information

Product Name	1,2-Piperidinedicarboxylic Acid, 6-Methyl-, 1-(1,1-Dimethylethyl) Ester (Wx610118)
CAS No.	661458-33-9
Molecular Formula	C13H23NO4
Molecular Weight	257.33 g/mol
Synonyms	1-(tert-Butyl) 2-methyl 6-methylpiperidine-1,2-dicarboxylate; tert-Butyl 2-(methoxycarbonyl)-6-methylpiperidine-1-carboxylate; 6-Methyl-1,2-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) 2-methyl ester; 1-Boc-6-methyl-piperidine-2-carboxylic acid methyl ester; Methyl 1-Boc-6-methylpipecolate; WX-610118; Wx610118
EINECS	Contact for details

Quality Control

Our 1,2-Piperidinedicarboxylic Acid, 6-Methyl-, 1-(1,1-Dimethylethyl) Ester is manufactured under a quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Specifications are designed to meet the stringent requirements of pharmaceutical R&D and can be aligned with cGMP standards for advanced projects upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.