Description

3,4-Piperidinediol, 1-Ethyl-, (3R,4R)-Rel- (9Ci) is a chiral piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking high-purity, stereochemically defined intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical reactions to introduce defined stereocenters into complex molecules.
• Agrochemical Research: Used in the synthesis of advanced, enantiomerically pure pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in homogeneous catalysis.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	3,4-Piperidinediol, 1-Ethyl-, (3R,4R)-Rel- (9Ci)
CAS No.	660403-83-8
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	(3R,4R)-1-Ethylpiperidine-3,4-diol; rel-(3R,4R)-1-Ethyl-3,4-piperidinediol; 1-Ethyl-3,4-piperidinediol (rel-(3R,4R)-); 3,4-Piperidinediol, 1-ethyl-, (3R,4R)-rel-; (3R,4R)-1-Ethyl-3,4-dihydroxypiperidine; 660403-83-8; 1-Ethyl-3,4-dihydroxypiperidine (rel-(3R,4R)-)
EINECS	Contact for details

Quality Control

Our 3,4-Piperidinediol, 1-Ethyl-, (3R,4R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.