Description

4-Pyridinecarbonitrile, 2-Chloro-3-(Hydroxy-1-Naphthalenylmethyl)- is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a pyridine core with chloro, cyano, and naphthyl-hydroxymethyl substituents, enabling precise structural modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Ligand Synthesis: Acts as a starting material for creating sophisticated chelating ligands used in catalysis or metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic electronic materials or advanced polymers due to its conjugated system and functional groups.
• Chemical Biology Probe Development: Utilized to build molecular probes for studying enzyme function or cellular processes.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry, including novel cross-coupling or cyclization reactions.

Basic Information

Product Name	4-Pyridinecarbonitrile, 2-Chloro-3-(Hydroxy-1-Naphthalenylmethyl)-
CAS No.	658695-47-7
Molecular Formula	C₁₇H₁₁ClN₂O
Molecular Weight	294.74 g/mol
Synonyms	2-Chloro-3-(hydroxy-1-naphthalenylmethyl)-4-pyridinecarbonitrile; 2-Chloro-3-[(1-hydroxynaphthalen-2-yl)methyl]isonicotinonitrile; 2-Chloro-3-[(1-hydroxy-2-naphthyl)methyl]isonicotinonitrile; 2-Chloro-3-(1-hydroxy-2-naphthylmethyl)pyridine-4-carbonitrile; 4-Cyano-2-chloro-3-(1-hydroxy-2-naphthylmethyl)pyridine; Isonicotinonitrile, 2-chloro-3-[(1-hydroxy-2-naphthyl)methyl]-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) documenting lot-specific results are available upon request. Our quality management system supports cGMP and ISO guidelines for reliable sourcing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is likely light-sensitive and may be hygroscopic; therefore, handling under an inert atmosphere is recommended for long-term storage or when working with large quantities.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.