Description

α-Tosyl-(3-Iodomethylbenzyl)Isocyanide CAS NO 655254-56-1 is a specialized organic building block featuring a unique combination of tosyl, iodomethyl, and isocyanide functional groups. This compound is highly valued in advanced organic synthesis for its versatility as a multi-functional reagent, enabling the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as multicomponent reactions and the synthesis of heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly for libraries targeting diverse biological pathways.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides by facilitating the creation of complex bioactive molecules.
• Material Science: Used in the preparation of functionalized polymers, ligands for catalysis, and advanced organic frameworks with tailored properties.
• Multicomponent Reaction (MCR) Chemistry: Serves as a critical component in Passerini and Ugi-type reactions to efficiently generate molecular diversity from simple starting materials.
• Chemical Biology & Probe Development: Utilized for synthesizing molecular probes and bioconjugation agents to study biological processes and protein interactions.
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new synthetic routes in organic chemistry laboratories worldwide.

Basic Information

Product Name	α-Tosyl-(3-Iodomethylbenzyl)Isocyanide
CAS No.	655254-56-1
Molecular Formula	C16H14INO2S
Molecular Weight	427.26 g/mol
Synonyms	1-Isocyano-2-(4-methylphenyl)sulfonyl-3-(iodomethyl)benzene; 3-(Iodomethyl)-α-tosylbenzyl isocyanide; α-Tosyl-3-iodomethylbenzyl isocyanide; (3-Iodomethylphenyl)(tosylmethyl)isocyanide; TosMIC Iodomethyl Benzyl Derivative; Tosylmethyl Isocyanide Iodobenzyl Analog
EINECS	Contact for details

Quality Control

Every batch of α-Tosyl-(3-Iodomethylbenzyl)Isocyanide is produced and tested under strict quality management protocols to ensure consistency and reliability for critical research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be moisture-sensitive. Keep container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.