Description

5-(Aminomethyl)-2-(n-Boc)Aminopyridine is a protected amine derivative of aminopyridine, serving as a crucial building block in organic synthesis. This compound matters for its role in constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) drug discovery.
• Peptidomimetic Synthesis: Used to introduce protected amino-functionalized pyridine moieties into peptide backbones to modulate biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for creating chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Scale-up: Employed in contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	5-(Aminomethyl)-2-(n-Boc)Aminopyridine
CAS No.	654679-12-6
Molecular Formula	C12H19N3O2
Molecular Weight	237.30 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-5-(aminomethyl)pyridine; 5-(Aminomethyl)-2-[(tert-butoxycarbonyl)amino]pyridine; tert-Butyl N-[5-(aminomethyl)pyridin-2-yl]carbamate; N-Boc-2-amino-5-aminomethylpyridine; Boc-2-Amino-5-aminomethylpyridine; 2-Amino-5-aminomethylpyridine N-Boc derivative; 5-(Aminomethyl)-2-(Boc-amino)pyridine
EINECS	Contact for details

Quality Control

Our 5-(Aminomethyl)-2-(n-Boc)Aminopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every lot and provided upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.