Description

Benzamide, n-[(6S)-6,7-Dihydro-5H-Cyclopenta[B]Pyridin-6-Yl]-4-Fluoro- (9Ci) is a high-purity, fluorinated benzamide derivative with a fused cyclopentapyridine core, representing a sophisticated chiral building block for advanced chemical synthesis. This compound is of significant value in pharmaceutical research and development, particularly for its potential role as a key intermediate in the creation of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or specialty molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Active Pharmaceutical Ingredient (API) Development: Used as a building block in the synthesis of complex API molecules, leveraging its fluorinated aromatic and constrained bicyclic structure to modulate biological activity and pharmacokinetic properties.
• Agrochemical Research: Acts as a precursor in the development of new generation herbicides, fungicides, or insecticides, where the fluorine atom and the benzamide moiety can enhance bioactivity and environmental stability.
• Chemical Biology & Probe Development: Employed in the design and synthesis of chemical probes for studying enzyme function or protein-protein interactions within biological systems.
• Process Chemistry & Scale-up: Used in route scouting and optimization studies for the efficient, large-scale manufacturing of target molecules, benefiting from its defined stereochemistry.
• Academic & Institutional Research: Provides a valuable tool for synthetic methodology development and the exploration of new chemical spaces in university and government laboratories.

Basic Information

Product Name	Benzamide, n-[(6S)-6,7-Dihydro-5H-Cyclopenta[B]Pyridin-6-Yl]-4-Fluoro- (9Ci)
CAS No.	654676-73-0
Molecular Formula	C15H13FN2O
Molecular Weight	256.28 g/mol
Synonyms	4-Fluoro-N-[(6S)-6,7-dihydro-5H-cyclopenta[b]pyridin-6-yl]benzamide; (S)-4-Fluoro-N-(6,7-dihydro-5H-cyclopenta[b]pyridin-6-yl)benzamide; N-[(6S)-6,7-Dihydro-5H-cyclopenta[b]pyridin-6-yl]-4-fluorobenzamide; 654676-73-0; Benzamide, 4-fluoro-N-[(6S)-6,7-dihydro-5H-cyclopenta[b]pyridin-6-yl]-; A fluorinated cyclopentapyridine benzamide derivative
EINECS	Contact for details

Quality Control

Our Benzamide, n-[(6S)-6,7-Dihydro-5H-Cyclopenta[B]Pyridin-6-Yl]-4-Fluoro- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.