Description

2-(3-Hydroxy-1-Pyrrolidinyl)Isonicotinic Acid is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and anti-infective research.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex molecular architectures containing the isonicotinic acid and pyrrolidine motifs.
• Research & Development (R&D): Serves as a standard or reagent in medicinal chemistry labs for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the production scale-up of specific APIs under controlled GMP environments.
• Bioconjugation Chemistry: Potential use in creating linker molecules for antibody-drug conjugates (ADCs) or other targeted therapies.

Basic Information

Product Name	2-(3-Hydroxy-1-Pyrrolidinyl)Isonicotinic Acid
CAS No.	654663-49-7
Molecular Formula	C10H12N2O3
Molecular Weight	208.22 g/mol
Synonyms	2-[(3-Hydroxypyrrolidin-1-yl)]isonicotinic Acid; 2-(3-Hydroxy-1-pyrrolidinyl)-4-pyridinecarboxylic Acid; 4-Pyridinecarboxylic acid, 2-(3-hydroxy-1-pyrrolidinyl)-; Isonicotinic acid, 2-(3-hydroxy-1-pyrrolidinyl)-; 654663-49-7; 2-(3-Hydroxypyrrolidin-1-yl)pyridine-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-(3-Hydroxy-1-Pyrrolidinyl)Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.