Description

2-Chloro-3-(3-Ethoxycarbonylbenzoyl)Pyridine is a high-purity organic intermediate featuring a pyridine core substituted with chlorophenyl and ester functional groups. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the development of organic ligands for catalysts or functional materials due to its aromatic and coordinating properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	2-Chloro-3-(3-Ethoxycarbonylbenzoyl)Pyridine
CAS No.	654059-12-8
Molecular Formula	C16H14ClNO3
Molecular Weight	303.74 g/mol
Synonyms	2-Chloro-3-(3-ethoxycarbonylbenzoyl)pyridine; 3-(2-Chloropyridine-3-carbonyl)benzoic acid ethyl ester; Ethyl 3-(2-chloronicotinoyl)benzoate; 2-Chloro-3-(3-carbethoxybenzoyl)pyridine; 654059-12-8; Ethyl 3-[(2-chloropyridin-3-yl)carbonyl]benzoate; Benzoic acid, 3-[(2-chloropyridin-3-yl)carbonyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(3-Ethoxycarbonylbenzoyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and we support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.