Description

Zanolimumab is a fully human monoclonal antibody designed for targeted therapeutic intervention. This high-purity biological agent is critical for research and development in advanced immunology and oncology. It is primarily utilized by pharmaceutical developers, biotechnology research institutions, and clinical laboratories focused on innovative treatment modalities.

Application

• Biopharmaceutical R&D: Serves as a key reference standard and active ingredient in the development of novel immunotherapies.
• Mechanism of Action Studies: Used in preclinical and clinical research to investigate specific immunological pathways and cellular responses.
• Process Development & Scale-up: Employed in the optimization of upstream and downstream manufacturing processes for monoclonal antibody production.
• Analytical Method Development: Acts as a critical material for validating bioanalytical assays, including potency, purity, and stability testing.
• Cell-Based Assays: Utilized in functional in vitro assays to evaluate efficacy and specificity against target antigens.

Basic Information

Product Name	Zanolimumab
CAS No.	652153-01-0
Molecular Formula	Contact for details
Molecular Weight	Approx. 145-150 kDa
Synonyms	HuMax-CD4; Anti-CD4 Monoclonal Antibody; Fully Human Anti-CD4 IgG1κ; Monoclonal Antibody CD4; Therapeutic Anti-CD4 Antibody; CD4 Inhibitor; TNX-355 (related investigational name); Anti-CD4
EINECS	Contact for details

Quality Control

Our Zanolimumab is manufactured under strict quality systems. Each batch is subjected to a comprehensive battery of analytical tests to ensure identity, purity, potency, and safety, aligning with ICH Q6B guidelines for biotechnological products. Certificates of Analysis (COA) documenting full specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. Refer to the specific Certificate of Analysis for detailed storage and handling instructions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear to slightly opalescent solution
Identification (HPLC/MS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0% Monomer
Assay (UV/Functional)	90.0% - 110.0% of label claim
Endotoxin	< 1.0 EU/mg
Host Cell Protein	< 100 ppm
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.