Description

5-Bromopyridine-2-Boronic Acid is a versatile and high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and agrochemical research. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific bromo- and boronic-substituted heterocycles.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: Serves as a pivotal boronic acid partner for coupling with various aryl/heteroaryl halides to form biaryl and heterobiaryl structures.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and biochemical tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis organizations (CSOs) and CROs serving the global life sciences market.

Basic Information

Product Name	5-Bromopyridine-2-Boronic Acid
CAS No.	652148-97-5
Molecular Formula	C5H5BBrNO2
Molecular Weight	201.82 g/mol
Synonyms	(5-Bromopyridin-2-yl)boronic acid; 2-Borono-5-bromopyridine; 5-Bromo-2-pyridineboronic acid; 5-Bromopyridine-2-boronic acid pinacol ester (common derivative); 5-Bromo-2-pyridinylboronic acid; B-(5-Bromo-2-pyridinyl)boronic acid; 652148-97-5 (CAS).
EINECS	Contact for details

Quality Control

Our 5-Bromopyridine-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.