Description

5-Chloropyridine-2-Boronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who are developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in modern herbicides, fungicides, and insecticides.
• Material Science: Employed in the development of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and inhibitors.
• Catalyst & Ligand Development: Serves as a building block for creating novel bidentate ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CROs/CMOs serving the life sciences sector.

Basic Information

Product Name	5-Chloropyridine-2-Boronic Acid
CAS No.	652148-91-9
Molecular Formula	C5H5BClNO2
Molecular Weight	157.36 g/mol
Synonyms	(5-Chloropyridin-2-yl)boronic acid; 5-Chloro-2-pyridineboronic acid; 2-Borono-5-chloropyridine; 5-Chloro-2-pyridinylboronic acid; 5-Chloropyridine-2-boronic acid pinacol ester (common derivative); 5-Cl-Py-2-B(OH)2; 5-Chloro-2-boronopyridine
EINECS	Contact for details

Quality Control

Our 5-Chloropyridine-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.