Description

Spiro[Cyclopropane-1,2(3H)-Indolizin]-7(1H)-One, Tetrahydro- (9Ci) is a sophisticated spirocyclic organic compound, identified by CAS NO 651736-89-9, that serves as a critical building block in advanced synthetic chemistry. This molecule is valued for its unique three-dimensional structure, which provides a rigid scaffold essential for modulating biological activity and material properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring complex molecular architectures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its spirocyclic core can contribute to unique modes of action and improved environmental profiles.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with specific thermal or optical properties.
• Chemical Biology: Employed as a molecular probe or scaffold in the study of protein-ligand interactions and enzyme mechanisms.
• Academic & Contract Research: Serves as a valuable reagent for methodological development in organic synthesis and catalysis research within universities and CROs.

Basic Information

Item	Details
Product Name	Spiro[Cyclopropane-1,2(3H)-Indolizin]-7(1H)-One, Tetrahydro- (9Ci)
CAS No.	651736-89-9
Molecular Formula	C11H13NO
Molecular Weight	175.23 g/mol
Synonyms	7H-Spiro[cyclopropane-1,2'-indolizin]-7-one, tetrahydro-; Tetrahydrospiro[cyclopropane-1,2(3H)-indolizin]-7(1H)-one; 651736-89-9; Spiro[cyclopropane-1,2-indolizin]-7-one, tetrahydro-; Spiro(cyclopropane-1,2-indolizin)-7-one, tetrahydro-; 1H-Spiro[cyclopropane-1,2'-indolizin]-7-one, octahydro-
EINECS	Contact for details

Quality Control

Every batch of Spiro[Cyclopropane-1,2(3H)-Indolizin]-7(1H)-One, Tetrahydro- (9Ci) is produced and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.