Description

Carbamic Acid, [(4Z)-5-Chloro-4-Penten-2-Ynyl]-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic building block featuring a unique chloroenyne structure protected by a tert-butyl carbamate (Boc) group. This compound matters as a high-value synthetic intermediate, offering precise control over molecular architecture for advanced chemical synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry programs targeting novel bioactive entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring a functionalized alkyne moiety for click chemistry or further derivatization.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where its chloro and alkyne functionalities can be leveraged to create unique bioactive scaffolds.
• Chemical Biology Probe Synthesis: The protected amine and reactive handles make it suitable for constructing molecular probes and tools for studying biological processes.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the research of specialty polymers with tailored properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for complex molecule construction, including natural product synthesis and methodology development.

Basic Information

Product Name	Carbamic Acid, [(4Z)-5-Chloro-4-Penten-2-Ynyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	651733-31-2
Molecular Formula	C10H14ClNO2
Molecular Weight	215.68 g/mol
Synonyms	tert-Butyl (Z)-5-chloropent-4-en-2-yn-1-ylcarbamate; N-Boc-5-chloro-4-penten-2-ynylamine; (Z)-5-Chloro-4-penten-2-ynyl tert-butylcarbamate; 1,1-Dimethylethyl [(4Z)-5-chloro-4-penten-2-ynyl]carbamate; Boc-protected 5-chloro-4-penten-2-ynylamine; (Z)-N-Boc-5-chloro-4-penten-2-yn-1-amine; tert-Butyl N-[(4Z)-5-chloropenta-4-en-2-yn-1-yl]carbamate
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(4Z)-5-Chloro-4-Penten-2-Ynyl]-, 1,1-Dimethylethyl Ester (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and MS. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is compatible with strong acid/organic solvent environments but should be kept away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid or clear to pale yellow liquid/oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Isomeric Purity (Z-isomer)	≥95%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.