Description

tert-Butyl 3-Fluoro-4-Phenyl-5,6-Dihydropyridine-1(2H)-Carboxylate is a high-value, fluorinated piperidine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a protected nitrogen scaffold and a versatile phenyl-fluoro substitution pattern, enabling the efficient construction of complex pharmacophores. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in neurological and psychiatric drug discovery.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage the fluorine atom for enhanced bioactivity and stability.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating labeled compounds or molecular probes to study biological pathways and protein interactions.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced organic materials with specific electronic properties.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 3-Fluoro-4-Phenyl-5,6-Dihydropyridine-1(2H)-Carboxylate
CAS No.	651321-26-5
Molecular Formula	C16H20FNO2
Molecular Weight	277.34 g/mol
Synonyms	1-Boc-3-fluoro-4-phenyl-1,2,3,6-tetrahydropyridine; tert-Butyl 3-fluoro-4-phenyl-3,6-dihydro-2H-pyridine-1-carboxylate; 3-Fluoro-4-phenyl-1,2,3,6-tetrahydropyridine-1-carboxylic acid tert-butyl ester; 1,2,3,6-Tetrahydro-3-fluoro-4-phenylpyridine-1-carboxylic acid tert-butyl ester; 1-N-Boc-3-fluoro-4-phenyl-1,2,3,6-tetrahydropyridine; Boc-3-fluoro-4-phenyl-DHP; 651321-26-5
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 3-Fluoro-4-Phenyl-5,6-Dihydropyridine-1(2H)-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is fully characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.